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Print/export Download as PDF; Printable version; In other projects ... DECIPHER is a software that can be used to decipher and manage biological sequences efficiently ...
The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...
DECIPHER is a web-based resource and database of genomic variation data from analysis of patient DNA. [ 1 ] [ 2 ] [ 3 ] It documents submicroscopic chromosome abnormalities ( microdeletions and duplications ) and pathogenic sequence variants (single nucleotide variants - SNVs, Insertions, Deletions, InDels), from over 25000 patients and maps ...
John Henry Holland was born on February 2, 1929 in Fort Wayne, Indiana, the elder child of [3] son of Gustave A. Holland (b. July 24, 1896, Russian Poland) and Mildred P. Gfroerer (b.
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. [1] More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access ...
Holland's schema theorem, also called the fundamental theorem of genetic algorithms, [1] is an inequality that results from coarse-graining an equation for evolutionary dynamics. The Schema Theorem says that short, low-order schemata with above-average fitness increase exponentially in frequency in successive generations.
SPHINX, [16] another binning algorithm developed by the Innovation Labs of Tata Consultancy Services (TCS) Ltd., adopts a hybrid strategy that achieves high binning efficiency by utilizing the principles of both 'composition'- and 'alignment'-based binning algorithms. The approach was designed with the objective of analyzing metagenomic ...
Nucleotide sequence analyses identify functional elements like protein binding sites, uncover genetic variations like SNPs, study gene expression patterns, and understand the genetic basis of traits. It helps to understand mechanisms that contribute to processes like replication and transcription. Some of the tasks involved are outlined below.