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Transitional epithelial cells, also known as urothelial cells, line the urinary tract from the renal pelvis through the ureters and bladder and, in males, the upper portion of the urethra. They are smaller than squamous cells and their shape varies based on the layer of epithelium from which they are derived, but they are most commonly round or ...
These cells appear to be cuboidal with a domed apex when the organ or the tube in which they reside is not stretched. When the organ or tube is stretched (such as when the bladder is filled with urine), the tissue compresses and the cells become stretched. When this happens, the cells flatten, and they appear to be squamous and irregular.
Urine typically contains epithelial cells shed from the urinary tract, and urine cytology evaluates this urinary sediment for the presence of cancerous cells [2] [3] from the lining of the urinary tract, and it is a convenient noninvasive technique for follow-up analysis of patients treated for urinary tract cancers.
A sample of urine sediment from a patient suffering from a urinary infection, it is possible to see leukocytes (small round and granular), erythrocytes (small round and biconcave) and epithelial cells (large and polyhedral). The test for leukocyte esterase is indicative and does not replace microscopic examination of urine.
The most common type of cast, hyaline casts are solidified Tamm–Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and as such, they may be seen in normal individuals in dehydration or vigorous exercise.
These are simple columnar epithelial cells whose nuclei appear at different heights, giving the misleading (hence "pseudo") impression that the epithelium is stratified when the cells are viewed in cross section. Ciliated pseudostratified epithelial cells have cilia. Cilia are capable of energy-dependent pulsatile beating in a certain direction ...
Decoy cells are virally infected epithelial cells that can be found in the urine. Decoy cells owe their name to their strong resemblance to cancer cells, and may as such confuse the diagnosis of either viral infection or urothelial malignancy. During 1950s, cytotechnologist Andrew Ricci observed cells mimicking cancer cells by they were not, in ...
Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. [1] Bowman's capsule filters the blood, retaining large molecules such as proteins while smaller molecules such as water, salts, and sugars are filtered as the first step in the formation of urine.