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Trimethyl phosphate is a mild methylating agent, useful for dimethylation of anilines and related heterocyclic compounds. [2] The method is complementary to the traditional Eschweiler-Clarke reaction in cases where formaldehyde engages in side reactions.
The general formula of a phosphoric acid is H n+2−2x P n O 3n+1−x, where n is the number of phosphorus atoms and x is the number of fundamental cycles in the molecule's structure, between 0 and n + 2 / 2 . Pyrophosphate anion. Trimethyl orthophosphate.
In organic chemistry, phosphate or orthophosphate is an organophosphate, an ester of orthophosphoric acid of the form PO 4 RR′R″ where one or more hydrogen atoms are replaced by organic groups. An example is trimethyl phosphate, (CH 3) 3 PO 4. The term also refers to the trivalent functional group OP(O-) 3 in such esters.
For example, the formula of methyl phosphate is CH 3-H 2 PO 4, dimethyl phosphate – (CH 3) 2 HPO 4 and trimethyl phosphate – (CH 3) 3 PO 4. Alkyl phosphates are widely distributed in nature, and form the basis of most biological processes. For example, high energy metabolites such as ATP and PEP are alkyl phosphates, as are nucleic acids ...
Trimethyl phosphite is an organophosphorus compound with the formula P(OCH 3) 3, often abbreviated P(OMe) 3.It is a colorless liquid with a highly pungent odor. It is the simplest phosphite ester and finds used as a ligand in organometallic chemistry and as a reagent in organic synthesis.
Trimethylphosphine is a highly basic ligand that forms complexes with most metals. As a ligand, trimethylphosphine's Tolman cone angle is 118°. [7] This angle is an indication of the amount of steric protection that this ligand provides to the metal that to which it is bound.
Trimethyl orthoformate (TMOF) is the organic compound with the formula HC(OCH 3) 3. A colorless liquid, it is the simplest orthoester. It is a reagent used in organic synthesis for the formation of methyl ethers. [3] The product of reaction of an aldehyde with trimethyl orthoformate is an acetal.
Monothiophosphate is used in research as an analogue of phosphate in biochemistry. Monothiophosphate esters are biochemical reagents used in the study of transcription, [4] substitution interference assays. Sometimes, "monothiophosphate" refers to esters such as (CH 3 O) 2 POS −. [5]