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Epidemiology Janet Elizabeth Lane-Claypon, Lady Forber JP (3 February 1877 – 17 July 1967) was an English physician. She was one of the founders of the science of epidemiology , pioneering the use of cohort studies and case-control studies .
Case series have a descriptive study design; unlike studies that employ an analytic design (e.g. cohort studies, case-control studies or randomized controlled trials), case series do not, in themselves, involve hypothesis testing to look for evidence of cause and effect (though case-only analyses are sometimes performed in genetic epidemiology ...
Epidemiological (and other observational) studies typically highlight associations between exposures and outcomes, rather than causation. While some consider this a limitation of observational research, epidemiological models of causation (e.g. Bradford Hill criteria) [7] contend that an entire body of evidence is needed before determining if an association is truly causal. [8]
Porta's Dictionary of Epidemiology defines the case–control study as: "an observational epidemiological study of persons with the disease (or another outcome variable) of interest and a suitable control group of persons without the disease (comparison group, reference group). The potential relationship of a suspected risk factor or an ...
Conversely, in experimental studies, the epidemiologist is the one in control of all of the factors entering a certain case study. [43] Epidemiological studies are aimed, where possible, at revealing unbiased relationships between exposures such as alcohol or smoking, biological agents , stress , or chemicals to mortality or morbidity .
This study was a retrospective, case-control study that compared smoking habits of 684 individuals with bronchogenic carcinoma to those without the condition. [12] The survey included questions about smoking: starting age, 20 year tobacco consumption, brands used; as well as inquires about exposure to hazardous agents in the workplace, alcohol use, and causes of death for family members.
[9] [10] Crucially, unlike the earlier studies, which were generally cross-sectional in design (statistical snapshots of large, anonymous populations taken at arbitrary times), the Harvard Six Cities was a cohort study that tracked the same people over their lives, so allowing risk factors such as age, sex, and smoking history to be eliminated ...
Epidemiology of cancer; Cancer survival rates; Case fatality rate; Case–control study; Causal pie model; Cause (medicine) Cause of death; Epidemiology of chikungunya; Epidemiology of childhood obesity; Clinical case definition; Clinical epidemiology; Cochran–Mantel–Haenszel statistics; Cognitive epidemiology; Cohort effect; Cohort study ...