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Specialty. Medical genetics. Distal 18q- is a genetic condition caused by a deletion of genetic material within one of the two copies of chromosome 18. [1] The deletion involves the distal section of 18q and typically extends to the tip of the long arm of chromosome 18. [2]
The ring is formed when the caps on both the long arm (q) and the short arm (p) of one copy of chromosome 18 are lost and the new ends re-join to form the ring. Because the ring involves deletions of both the long arm (18q-) and the short arm (18p-) of chromosome 18, individuals with ring 18 can have features of both 18p-as well as distal 18q-.
Krukenberg tumors often come to the attention when they cause abdominal or pelvic pain, bloating, ascites, or pain during sexual intercourse.Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in vaginal bleeding, a change in menstrual habits, or hirsutism, [3] or occasionally virilization [4] as a main symptom.
Papillomatosis of the breast (PB) is a rare, benign, epitheliosis-like lesion, i.e. an overgrowth of the cells lining the ducts of glands that resembles a papilla (i.e. small rounded protuberance) or nipple -like nodule/tumor. PB tumors develop in the apocrine glands of the breast. [ 1 ][ 2 ] PB is also termed juvenile papillomatosis because of ...
Breast cancer. Breast cancer is cancer of the breast tissues, most commonly arising from the milk ducts. Worldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases. [5] It is most common in women over age 50. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the ...
Breast pain. Breast pain is the symptom of discomfort in either one or both breasts. [2] Pain in both breasts is often described as breast tenderness, is usually associated with the menstrual period and is not serious. [1][3] Pain that involves only one part of a breast is more concerning, [1] particularly if a hard mass or nipple discharge is ...
Trisomy 18, also known as Edwards syndrome, is a genetic disorder caused by the presence of a third copy of all or part of chromosome 18. [3] Many parts of the body are affected. [ 3 ] Babies are often born small and have heart defects . [ 3 ]
Alveolar rhabdomyosarcoma (ARMS) is a subtype of the rhabdomyosarcoma family of soft tissue cancers whose lineage is from mesenchymal cells and are related to skeletal muscle cells. [1] ARMS tumors resemble the alveolar tissue in the lungs. [1] Tumor location varies from patient to patient, but is commonly found in the head and neck region ...