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When an unusual cluster of illness is noted, infection control teams undertake an investigation to determine whether there is a true disease outbreak, a pseudo-outbreak (a result of contamination within the diagnostic testing process), or just random fluctuation in the frequency of illness. If a true outbreak is discovered, infection control ...
Epidemiological (and other observational) studies typically highlight associations between exposures and outcomes, rather than causation. While some consider this a limitation of observational research, epidemiological models of causation (e.g. Bradford Hill criteria) [7] contend that an entire body of evidence is needed before determining if an association is truly causal. [8]
The order of the above steps and relative amount of effort and resources used in each varies from outbreak to outbreak. [3] For example, prevention and control measures are usually implemented very early in the investigation, often before the causative agent is known.
The Bradford Hill criteria, otherwise known as Hill's criteria for causation, are a group of nine principles that can be useful in establishing epidemiologic evidence of a causal relationship between a presumed cause and an observed effect and have been widely used in public health research.
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Outbreak response or outbreak control measures are acts which attempt to minimize the spread of or effects of a disease outbreak.Outbreak response includes aspects of general disease control such as maintaining adequate hygiene, but may also include responses that extend beyond traditional healthcare settings and are unique to an outbreak, such as physical distancing, contact tracing, mapping ...
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Common source outbreak of Hepatitis A in Nov-Dec 1978. This epidemic curve shows a presumed first case, known as the index case on November 6, 1978. 4 days later, there was a steep increase in cases, followed by the curve tapering down to zero. Some cases were food handlers, and some secondary cases.