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In linear algebra, the Hermite normal form is an analogue of reduced echelon form for matrices over the integers Z.Just as reduced echelon form can be used to solve problems about the solution to the linear system Ax=b where x is in R n, the Hermite normal form can solve problems about the solution to the linear system Ax=b where this time x is restricted to have integer coordinates only.
Protein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. [1] Proteins can be designed from scratch (de novo design) or by making calculated variants of a known protein structure and its sequence (termed protein redesign).
An alpha-helix with hydrogen bonds (yellow dots) The α-helix is the most abundant type of secondary structure in proteins. The α-helix has 3.6 amino acids per turn with an H-bond formed between every fourth residue; the average length is 10 amino acids (3 turns) or 10 Å but varies from 5 to 40 (1.5 to 11 turns).
Residues that are conserved across all sequences are highlighted in grey. Below each site (i.e., position) of the protein sequence alignment is a key denoting conserved sites (*), sites with conservative replacements (:), sites with semi-conservative replacements (.), and sites with non-conservative replacements ( ). [1]
A rewriting system has the unique normal form property (UN) if for all normal forms a, b ∈ S, a can be reached from b by a series of rewrites and inverse rewrites only if a is equal to b. A rewriting system has the unique normal form property with respect to reduction (UN →) if for every term reducing to normal forms a and b, a is equal to ...
The sixth normal form is currently as of 2009 being used in some data warehouses where the benefits outweigh the drawbacks, [9] for example using anchor modeling.Although using 6NF leads to an explosion of tables, modern databases can prune the tables from select queries (using a process called 'table elimination' - so that a query can be solved without even reading some of the tables that the ...
The mRNA transcript of the ENO1 gene can be alternatively translated into a cytoplasmic protein, with a molecular weight of 48 kDa, or a nuclear protein, with a molecular weight of a 37 kDa. [ 9 ] [ 10 ] The nuclear form was previously identified as Myc-binding protein-1 (MBP1), which downregulates the protein level of the c-myc protooncogene ...
Protein primary structure is the linear sequence of amino acids in a peptide or protein. [1] By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end. Protein biosynthesis is most commonly performed by ribosomes in cells. Peptides can also be synthesized in the ...