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Valproate has a broad spectrum of anticonvulsant activity, although it is primarily used as a first-line treatment for tonic–clonic seizures, absence seizures and myoclonic seizures and as a second-line treatment for partial seizures and infantile spasms.
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]
The NRC's definition of dose equivalent is "the product of the absorbed dose in tissue, quality factor, and all other necessary modifying factors at the location of interest." However, it is apparent from their definition of effective dose equivalent that "all other necessary modifying factors" excludes the tissue weighting factor. [ 17 ]
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The RBRVS for each CPT code is determined using three separate factors: physician work, practice expense, and malpractice expense. The average relative weights of these are: physician work (52%), practice expense (44%), malpractice expense (4%). [2] A method to determine the physician work value was the primary contribution made by the Hsiao study.
The evidence for harm to people who are deprived of sleep, or work irregular hours, is robust. Research from Europe and the United States on nonstandard work hours and sleep deprivation found that late-hour workers are subject to higher risks of gastrointestinal disorders, cardiovascular disease, breast cancer, miscarriage, preterm birth, and low birth weight of their newborns.
Using the factor rate provided by the lender, you can quickly calculate the cost of the borrowed funds. For example, if you borrowed $100,000 with a factor rate of 1.5, multiply those two figures ...
Conversion of units is the conversion of the unit of measurement in which a quantity is expressed, typically through a multiplicative conversion factor that changes the unit without changing the quantity. This is also often loosely taken to include replacement of a quantity with a corresponding quantity that describes the same physical property.