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In July 2024, the US Food and Drug Administration (FDA) approved Felanorm, the first generic methimazole oral solution for the treatment of hyperthyroidism in cats. [26] [27] [28] Felanorm contains the same active ingredient (methimazole) as the approved brand name drug product, Felimazole Coated Tablets, which were first approved in May 2009. [26]
A systematic review from 2016 found that metamizole significantly increased the relative risk of upper gastrointestinal bleeding, by a factor of 1.4–2.7 times. [31] A study by one of the manufacturers of the drug found the risk of agranulocytosis within the first week of treatment to be a 1.1 in a million, versus 5.9 in a million for diclofenac .
Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 . It is on the World Health Organization's List of Essential Medicines.
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"Cool for Cats" is a song by English rock band Squeeze, released as the second single from their album of the same name. The song features a rare lead vocal performance from cockney-accented Squeeze lyricist Chris Difford , one of the only two occasions he sang lead on a Squeeze single A-side (the other was 1989's " Love Circles ").
"Levitating" is a song by English and Albanian singer Dua Lipa from her second studio album, Future Nostalgia (2020). The song was written by Lipa, Clarence Coffee Jr., Sarah Hudson, and Koz, who produced the song with Stuart Price, and stemmed from a Roland VP-330 synthesizer sample played by Koz.
Top view of Sony PVM-4300 with calico cat for scale A practical limit on the size of a CRT is the weight of the thick glass needed to safely sustain its vacuum, [ 355 ] since a CRT's exterior is exposed to the full atmospheric pressure , which for instance totals 5,800 pounds-force (26,000 N ) on a 27-inch (400 in 2 ) screen. [ 356 ]
The site's consensus reads, "A grim, gritty, and gripping super-noir, The Batman ranks among the Dark Knight's bleakest – and most thrillingly ambitious – live-action outings". [369] Metacritic, which uses a weighted average, assigned the film a score of 72 out of 100, based on 68 critics, indicating "generally favorable" reviews. [370]