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Neomycin B is the most active component in neomycin followed by neomycin C and neomycin A. Neomycin A is an inactive degradation product of the C and B isomers. [30] The quantities of these components in neomycin vary from lot-to-lot depending on the manufacturer and manufacturing process.
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. [ 2 ] [ 3 ] It consists of the antibiotics neomycin and polymyxin B , and the steroid hydrocortisone . [ 3 ]
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. [1] While it is useful for many Gram negative infections, it is not useful for Gram positive infections. [1]
Neamine (neomycin A) is a degradation product of the aminoglycoside antibiotic neomycin. [1] Several derivatives of neamine are active against susceptible and resistant Gram-positive and Gram-negative bacteria .
Though Polysporin is marketed in the US, it holds a much smaller market share than in Canada and acts as a substitute to Johnson & Johnson's Neosporin for those allergic to the antibiotic neomycin. However, allergy to bacitracin/polymyxin B has also been reported. [2] There is also an ophthalmological ointment, eye and ear drops.
This page was last edited on 6 December 2024, at 23:21 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Beta-propiolactone, egg protein, neomycin, nonylphenol ethoxylate, polymyxin, thimerosal (multi-dose containers), thimerosal [4] (single-dose syringes) Influenza vaccine ( Fluzone ) Egg protein, formaldehyde , gelatin (standard formulation only), octylphenol ethoxylate (Triton X-100), sodium phosphate , thimerosal (multi-dose containers only)