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  2. Efgartigimod alfa - Wikipedia

    en.wikipedia.org/wiki/Efgartigimod_alfa

    Efgartigimod alfa as a drug is an antibody fragment that binds to the neonatal Fc receptor. When this binding happens, the IgG recycling process is blocked. The amount of circulating IgG decreases and therefore prevents the acetylcholine receptors from being degraded by the autoantibodies that are responsible for the myasthenia gravis. [14]

  3. Cartesian Therapeutics Announces Positive Updated Results ...

    lite.aol.com/tech/story/0022/20241203/9312598.htm

    About Myasthenia Gravis . Myasthenia gravis (MG) is a chronic autoimmune disorder that causes disabling muscle weakness and fatigue. For most people with MG, the disease is characterized by the presence of antibodies against the acetylcholine receptor, a protein found on the surface of nerve cells that plays a key role in muscle contraction.

  4. Rozanolixizumab - Wikipedia

    en.wikipedia.org/wiki/Rozanolixizumab

    Rozanolixizumab, sold under the brand name Rystiggo, is a monoclonal antibody used for the treatment of myasthenia gravis. [1] Rozanolixizumab is a humanized and chimeric monoclonal antibody; [4] and is a neonatal Fc receptor blocker.

  5. Myasthenia gravis is one of the rarest and most concerning ...

    www.aol.com/myasthenia-gravis-one-rarest-most...

    Myasthenia gravis, or MG, is a chronic autoimmune neuromuscular disorder that causes muscle weakness and fatigue. ... it's often treated by administering one of five FDA-approved medications ...

  6. Myasthenia gravis - Wikipedia

    en.wikipedia.org/wiki/Myasthenia_gravis

    Myasthenia gravis affects 50 to 200 people per million. [3] [4] It is newly diagnosed in 3 to 30 people per million each year. [13] Diagnosis has become more common due to increased awareness. [13] Myasthenia gravis most commonly occurs in women under the age of 40 and in men over the age of 60. [1] [5] [14] It is uncommon in children. [1]

  7. Amgen (AMGN) Q4 2024 Earnings Call Transcript - AOL

    www.aol.com/amgen-amgn-q4-2024-earnings...

    The FDA also granted orphan drug designation to UPLIZNA for the treatment of generalized myasthenia gravis, based upon 26-week data from the Phase 3 MINT study.

  8. Neostigmine - Wikipedia

    en.wikipedia.org/wiki/Neostigmine

    Neostigmine, sold under the brand name Bloxiverz, among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. [ 3 ] [ 4 ] It is also used in anaesthesia to end the effects of non-depolarising neuromuscular blocking medication . [ 3 ]

  9. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    Eculizumab, sold under the brand name Soliris among others, is a recombinant humanized monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica.

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