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The bulboid corpuscles (end-bulbs of Krause, Krause corpuscles) are cutaneous receptors in humans and other animals. The end-bulbs of Krause were named after the German anatomist Wilhelm Krause (1833–1910). [1] [2]
This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement. [3] They are at the highest density around the fingernails where they act in monitoring slippage of objects along the surface of the skin, allowing modulation of grip on an object.
Krause discovered and described mechanoreceptors that were to become known as "Krause's corpuscles", sometimes referred to as "Krause's end-bulbs". [citation needed] His name is also associated with: "Krause's membranes": defined as isotropic bands in striated muscle fiber that consist of disks of sarcoplasm and connect the individual fibrils ...
Merkel nerve endings have a widely distributed in glabrous and hairy skin, in hair follicles, and in oral and anal mucosa. [citation needed]Meckel nerve endings are most numerous beneath the ridges of the fingertips which make up fingerprints, and less so in the palms and forearm.
The end-bulb of Krause or bulboid corpuscle detects temperatures above body temperature. Ruffini's end organ detects temperatures below body temperature. TRPV1 is a heat-activated channel that acts as a small heat detecting thermometer in the membrane which begins the polarization of the neural fiber when exposed to changes in temperature.
Skin appendages (or adnexa of skin) are anatomical skin-associated structures that serve a particular function including sensation, contractility, lubrication and heat loss in animals.
Bachmann's bundle – Jean George Bachmann (1877–1959), German-American physiologist; Balbiani bodies – Édouard-Gérard Balbiani; Bartholin's gland – Caspar Bartholin the Younger (1655–1738), Danish anatomist
[3] 20 to 40 glands of Krause are found in the upper fornix, and 6-8 glands appear in the lower fornix. [4] There are usually 2 to 5 Ciaccio's glands, and are found along the superior tarsal border of the upper eyelid. [1] Popov’s glands are located within the substance of the caruncle. [1]