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  2. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    This document provides principles physicians and researchers must consider when involving humans as research subjects. The Statement on Gene Therapy Research initiated by the Human Genome Organization (HUGO) in 2001, provides a legal baseline for all countries. HUGO's document emphasizes human freedom and adherence to human rights, and offers ...

  3. Jesse Gelsinger - Wikipedia

    en.wikipedia.org/wiki/Jesse_Gelsinger

    Both Wilson and the University are reported to have had financial stakes in the research. [4] [5] After his death, all gene therapy trials in the United States halted for a time. [6] The Gelsinger case was a severe setback for scientists working in the field and a reminder of the risks involved. [7]

  4. Human genetic enhancement - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_enhancement

    With the discovery of various types of immune-related disorders, there is a need for diversification in prevention and treatment. Developments in the field of gene therapy are being studied to be included in the scope of this treatment, but of course more research is needed to increase the positive results and minimize the negative effects of gene therapy applications. [27]

  5. List of gene therapies - Wikipedia

    en.wikipedia.org/wiki/List_of_gene_therapies

    This page was last edited on 10 November 2024, at 06:28 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  6. Gene therapy for color blindness - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_for_color...

    The first retinal gene therapy to be approved by the FDA was Voretigene neparvovec in 2017, which treats Leber's congenital amaurosis, a genetic disorder that can lead to blindness. These treatments also use subretinal injections of AAV vector and are therefore foundational to research in gene therapy for color blindness. [2] [3]

  7. Vectors in gene therapy - Wikipedia

    en.wikipedia.org/wiki/Vectors_in_gene_therapy

    How vectors work to transfer genetic material. Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).

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  9. Gene therapy of the human retina - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_of_the_human...

    Retinal gene therapy holds a promise in treating different forms of non-inherited and inherited blindness. In 2008, three independent research groups reported that patients with the rare genetic retinal disease Leber's congenital amaurosis had been successfully treated using gene therapy with adeno-associated virus (AAV).

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