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Dexamethasone is commonly given as a treatment for croup in children. [25] A single dose can reduce the swelling of the airway to improve breathing and reduce discomfort. [25] Dexamethasone is sometimes injected into the heel when treating plantar fasciitis or heel pain, sometimes in conjunction with triamcinolone acetonide. There is no ...
Croup is usually treated with a single dose of steroids by mouth. [2] [7] In more severe cases inhaled epinephrine may also be used. [2] [8] Hospitalization is required in one to five percent of cases. [9] Croup is a relatively common condition that affects about 15% of children at some point. [4]
It contains a wide range of information and advice on prescribing for children - from newborn to adolescence. The entries are classified by group of drug, giving cautions for use, side effects, indications and dose for most of the drugs available for children in the UK National Health Service. It also includes information on the unlicensed uses ...
Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects. Contrary to ciclosporin and tacrolimus, drugs that affect the first phase of T lymphocyte activation, sirolimus affects the second phase, namely signal transduction and lymphocyte clonal proliferation.
Hydrocortisone is a corticosteroid that is clinically used to relieve the pain and discomfort of mouth ulcers and functions to speed the healing of mouth ulcers. [citation needed] Common side effects include: oral thrush, visual disturbances (e.g. blurry vision), worsening of diabetes, worsening of mouth infections, and allergic reactions (e.g. skin rash).
Perioral dermatitis: This is a rash that occurs around the mouth and the eye region that has been associated with topical steroids. Ocular effects: Topical steroid drops are frequently used after eye surgery but can also raise intraocular pressure (IOP) and increase the risk of glaucoma , cataract , retinopathy as well as systemic adverse effects.
Low-dose and high-dose variations of the test exist. [4] The test is given at low (usually 1–2 mg) and high (8 mg) doses of dexamethasone, and the levels of cortisol are measured to obtain the results. [5] A low dose of dexamethasone suppresses cortisol in individuals with no pathology in endogenous cortisol production.
The therapeutic ratio in radiotherapy for cancer treatment is determined by the maximum radiation dose for killing cancer cells and the minimum radiation dose causing acute or late morbidity in cells of normal tissues. [13] Both of these parameters have sigmoidal dose–response curves. Thus, a favorable outcome in dose–response for tumor ...