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  2. MethDB - Wikipedia

    en.wikipedia.org/wiki/MethDB

    This Biological database -related article is a stub. You can help Wikipedia by expanding it.

  3. DNA methylation - Wikipedia

    en.wikipedia.org/wiki/DNA_methylation

    DNA methylation provides a relatively good means of sensitivity when identifying and detecting body fluids. In one study, only ten nanograms of a sample was necessary to ascertain successful results. [128] DNA methylation provides a good discernment of mixed samples since it involves markers that give "on or off" signals.

  4. DNA (cytosine-5)-methyltransferase 3A - Wikipedia

    en.wikipedia.org/wiki/DNA_(cytosine-5)-methyl...

    DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation. The enzyme is encoded in humans by the DNMT3A gene. [5] [6] This enzyme is responsible for de novo DNA methylation. Such function is to be distinguished from maintenance ...

  5. Methyltransferase - Wikipedia

    en.wikipedia.org/wiki/Methyltransferase

    2'-O-methylation, m6A methylation, m1G methylation as well as m5C are most commonly methylation marks observed in different types of RNA. 6A is an enzyme that catalyzes chemical reaction as following: [9] S-adenosyl-L-methionine + DNA adenine S-adenosyl-L-homocysteine + DNA 6-methylaminopurine

  6. DNMT1 - Wikipedia

    en.wikipedia.org/wiki/DNMT1

    DNA (cytosine-5)-methyltransferase 1 (Dnmt1) is an enzyme that catalyzes the transfer of methyl groups to specific CpG sites in DNA, a process called DNA methylation. In humans, it is encoded by the DNMT1 gene. [5] Dnmt1 forms part of the family of DNA methyltransferase enzymes, which consists primarily of DNMT1, DNMT3A, and DNMT3B.

  7. DNA-binding domain - Wikipedia

    en.wikipedia.org/wiki/DNA-binding_domain

    A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA. A DBD can recognize a specific DNA sequence (a recognition sequence) or have a general affinity to DNA. [1] Some DNA-binding domains may also include nucleic acids in their folded ...

  8. Methylated-DNA-protein-cysteine methyltransferase - Wikipedia

    en.wikipedia.org/wiki/Methylated-DNA-protein-cys...

    Overall, MGMT methylation is associated with prolonged patient survival in clinical prediction models. [10] For testing of the MGMT promoter methylation status in the clinical setting, DNA-based methods such as methylation-specific polymerase chain reaction (MS-PCR) or pyrosequencing are preferred over immunohistochemical or RNA- based assays. [11]

  9. DNA methyltransferase - Wikipedia

    en.wikipedia.org/wiki/DNA_methyltransferase

    For example, they indicated that H3K4me3 appears to block DNA methylation while H3K9me3 plays a role in promoting DNA methylation. DNMT3L [ 26 ] is a protein closely related to DNMT3a and DNMT3b in structure and critical for DNA methylation, but appears to be inactive on its own.