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A number of important medical conditions are caused by stones: [citation needed] Nephrolithiasis (kidney stones) Can cause hydronephrosis (swollen kidneys) and kidney failure; Can predispose to pyelonephritis (kidney infections) Can progress to urolithiasis; Urolithiasis (urinary bladder stones) Can progress to bladder outlet obstruction
What causes a kidney stone? There are a number of things that form kidney stones. Those with diseases like high blood pressure, diabetes, and obesity have a higher risk of having kidney stones.
Kidney stone disease; Other names: Urolithiasis, kidney stone, renal calculus, nephrolith, kidney stone disease, [1] A kidney stone, 8 millimeters (0.3 in) in diameter: Specialty: Urology, nephrology: Symptoms: Severe pain in the lower back or abdomen, blood in the urine, vomiting, nausea [2] Causes: Genetic and environmental factors [2 ...
Intrinsic kidney diseases are the classic diseases of the kidney including drug toxicity and nephritis. Post-renal kidney failure is outlet obstruction after the kidney, such as a kidney stone or prostatic bladder outlet obstruction. Kidney failure may require medication, dietary lifestyle modifications, and dialysis.
Kidney stones are caused by high levels of the minerals calcium, oxalate, and phosphorus in urine. These minerals are normally found in urine and do not cause problems at low levels.
The signs and symptoms of hydronephrosis depend upon whether the obstruction is acute or chronic, partial or complete, unilateral or bilateral.Hydronephrosis that occurs acutely with sudden onset (as caused by a kidney stone) can cause intense pain in the flank area (between the hips and ribs) known as a renal colic.
Type I xanthinuria can be caused by a deficiency of xanthine oxidase, which is an enzyme necessary for converting xanthine to uric acid. [2] Type II xanthinuria and molybdenum cofactor deficiency lack one or two other enzyme activities in addition to xanthine oxidase.
However, the increased uric acid levels in urine can contribute to kidney stones. Thus, use of these drugs is contraindicated in persons already with a high urine concentration of uric acid (hyperuricosuria). In borderline cases, enough water to produce 2 liters of urine per day may be sufficient to permit use of an uricosuric drug.
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