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Scar tissue is composed of the same protein as the tissue that it replaces, but the fiber composition of the protein is different; instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction. [1]
Granulation tissue is composed of tissue matrix supporting a variety of cell types, [3] most of which can be associated with one of the following functions: formation of extracellular matrix; operation of the immune system; vascularisation; An excess of granulation tissue (caro luxurians) is informally referred to as "proud flesh". [4]
They are usually replaced by the fibrous tissue. The result is the formation of an inflexible, fibrous scar tissue. Human skin cells are capable of repairing UV-induced DNA damages by the process of nucleotide excision repair. [2] This repair process protects against skin cancer. [2]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue. [1] [2]
Clavus papillari – a painful corn surrounded by a white border, which is either bruised or gelatinous tissue Clavus neurofibrosus (or fibrosus) – an old, deep scarred corn (in a crater with a white, sometimes macerated border) that is traversed by nerves and connective tissue, thought to be scar tissue caused by chronic low-grade inflammation.
Tattoo ink (or similar agent) is rubbed into a fresh cut to add color or extra visibility to the scar. Most of the ink remains in the skin as the cut heals. This was how tattoos were initially done before the use of needles to inject ink. [17] Skin removal/skinning Skin removal allows for larger markings than simple cutting.
Abrasions on elbow and lower arm. The elbow wound will produce a permanent scar. A first-degree abrasion involves only epidermal injury. A second-degree abrasion involves the epidermis as well as the dermis and may bleed slightly. A third-degree abrasion involves damage to the subcutaneous layer and the skin and is often called an avulsion.