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Diphenhydramine is a potent antimuscarinic (a competitive antagonist of muscarinic acetylcholine receptors) and, as such, at high doses can cause anticholinergic syndrome. [68] The utility of diphenhydramine as an antiparkinson agent is the result of its blocking properties on the muscarinic acetylcholine receptors in the brain.
The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [11] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side effect of drowsiness brought on by diphen ...
When it comes to weight loss supplements for women, there’s a lot out there you’re going to want to avoid. Fortunately, a few dietary supplements show some potential. Here’s what might help.
The typical adult gains an average of 1 to 2 pounds per year, which over time, can contribute to obesity. This weight gain can be driven by physical inactivity, stress, poor sleep and poor food ...
At the 1-year and 2-year marks compared to sertraline, bupropion’s estimations for weight gain were still lower. Escitalopram was still associated with weight gain after 1 year but not after 2 ...
The most common symptom associated with bloating is a sensation that the abdomen is full or distended. Rarely, bloating may be painful or cause shortness of breath. [citation needed] Pains that are due to bloating will feel sharp and cause the stomach to cramp. These pains may occur anywhere in the body and can change locations quickly. [8]
Researchers analyzed the weights of more than 183,000 adult antidepressant users six months, a year and two years after they started taking the drugs.
An FAA report found that between 2012 and 2016, diphenhydramine was the most common pharmaceutical known to cause impairment detected in post-mortem toxicology tests performed on someone who may have been in charge of the aircraft at the time of a fatal plane crash, specifically naming both Benadryl and Sominex. [65]