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Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.
Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. [7] It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. [8]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances , both toxic chemicals and medications , on kidney function . [ 1 ] There are various forms, [ 2 ] and some drugs may affect kidney function in more than one way.
Young women are most often affected. Infants and the elderly are also at increased risk, reflecting anatomical changes and hormonal status. [36] Xanthogranulomatous pyelonephritis is most common in middle-aged women. [25] It can present somewhat differently in children, in whom it may be mistaken for Wilms' tumor. [37]
Interstitial nephritis is uncommon (<1% incidence) in patients without any symptoms but occurs in about 10-15% of hospitalized patients with acute kidney injury of unknown cause. [2] While it can occur in patients of all ages, it is more common in elderly patients, perhaps due to increased exposure to drugs and other triggering causes. [2]
They are more common in women than men, but similar between anatomies while carrying indwelling catheters. [7] [18] In women, they are the most common form of bacterial infection. [19] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime.
He was convicted of killing two elderly women, including Harris, NBC5 reported. Chemirmir, 50, was found murdered in his Texas prison cell by his cellmate in September 2023, per the Associated Press .
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a rare cause of SJS in adults; the risk is higher for older patients, women, and those initiating treatment. [27] Typically, the symptoms of drug-induced SJS arise within a week of starting the medication. Similar to NSAIDs, paracetamol (acetaminophen) has also caused rare cases [28] [29] of SJS.