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Disseminated disease can refer to disseminated cancer which is the movement of cancerous cells from the original tumor to other areas of the body, [1] or disseminated infection which is the pathogen's entry into the host, growth, and dissemination, which results in illness. [2] After exiting the main tumor, cancer cells circulate throughout the ...
Carcinosis, or carcinomatosis, is disseminated cancer, forms of metastasis, ... Breast cancer, lung cancer and melanoma are the most common tumors. [8] Treatment
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
For example, metastatic cancer found in the upper body is more likely to have an origin above the diaphragm, at sites such as the lung and breast. If the metastatic cancer appears first in the lower part of the body, the primary cancer is more likely to be at sites below the diaphragm, such as the pancreas and liver. [9]
This means that if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer. Metastasis is a key element in cancer staging systems such as the TNM staging system, where it represents the "M".
Disseminating cancer cells can proliferate or become dormant depending on the microenvironment and factors such as the ERK/p38 ratio. Dormancy is a stage in cancer progression where the cells cease dividing but survive in a quiescent state while waiting for appropriate environmental conditions to begin proliferation again. [1]
In breast cancer patients, if micrometastases are present in the SLN, removal of these nodes is often the next step in treatment. Axillary lymph node dissection involves the excision of the nodes from the armpit, or axilla, region. Depending on the progression of the cells, the surgeon will determine the level of dissection that is required.
By the degree of invasion, a cancer can be classified as in situ when malignant cells are present as a tumor but have not metastasized, or invaded beyond the layer or tissue type where it arose. For example, a cancer of epithelial origin with such features is called carcinoma in situ, and is defined as not having invaded beyond the basement ...