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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
In all athletic programs, three features should be present: (1) emphasizing prolonged lower-intensity exercise, as opposed to repetitive max intensity exercises; (2) adequate rest periods and a high-carbohydrate diet, to replenish glycogen stores; and (3) proper hydration, to enhance renal clearance of myoglobin. [18]
Prolonged exercise such as marathons can increase cardiac biomarkers such as troponin, B-type natriuretic peptide (BNP), and ischemia-modified (aka MI) albumin. This can be misinterpreted by medical personnel as signs of myocardial infarction, or cardiac dysfunction. In these clinical conditions, such cardiac biomarkers are produced by ...
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." There are about as many performance supplements on the market as there are protein-packed foods in a ...
The stress induced during exercise results in an increase in the hormones, epinephrine and norepinephrine, which are known for the body's "fight or flight" response. Increased secretion of catecholamines are a hormone response regulated by the sympathoadrenal system (SAS) and the hypothalamic-pituitary-adrenal axis (HPAA). [ 10 ]
Just 1.5 to 4 minute small bursts of high intensity exercise throughout the day may lower a person’s risk of major cardiovascular events, such as stroke. ... time commitment, or traveling to a ...
The drug formulation (immediate release, excipients used, manufacturing methods, modified release – delayed release, extended release, sustained release, etc.) Whether the formulation is administered in a fed or fasted state; Gastric emptying rate; Circadian differences; Interactions with other drugs/foods: