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Vitamin D3. Is called cholecalciferol. ... age the recommended daily dose is 600 IU, but Dr. Manson’s research indicates that it is safe to take 1000-2000 IU a day “as a type of insurance ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Vitamin D 3 (cholecalciferol) is produced industrially by exposing 7-dehydrocholesterol to UVB and UVC light, followed by purification. The 7-dehydrocholesterol is sourced as an extraction from lanolin, a waxy skin secretion in sheep's wool. [189] Vitamin D 2 (ergocalciferol) is produced in a similar way using ergosterol from yeast as a ...
At a typical intake of cholecalciferol (up to 2000 IU/day), conversion to calcifediol is rapid. When large doses are given (100,000 IU), it takes 7 days to reach peak calcifediol concentrations. [9] Calcifediol binds in the blood to vitamin D-binding protein (also known as gc-globulin) and is the main circulating vitamin D metabolite.
The two most common forms are vitamin D2 and vitamin D3. Vitamin D is a fat-soluble vitamin which plays a major role in bone health, immunity, and nerve communication between the brain and muscle ...
There are two sources of vitamin D: Vitamin D2 comes from fortified foods and mushrooms, while vitamin D3 is produced in the skin when exposed to sunlight (which is why it’s often known as the ...
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