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Acute alcohol poisoning is a medical emergency due to the risk of death from respiratory depression or aspiration of vomit if vomiting occurs while the person is unresponsive. Emergency treatment strives to stabilize and maintain an open airway and sufficient breathing while waiting for the alcohol to metabolize.
In clinical studies, metadoxine has been reported to reduce the half-life of ethanol in healthy volunteers and in acutely intoxicated patients; to accelerate the metabolism of alcohol and acetaldehyde into less toxic higher ketones and to improve their urinary clearance; to restore laboratory variables such as alcohol, ammonia, γ-GT, and alanine aminotransferase; and to improve clinical ...
A sobering center is a facility or setting providing short-term (4-12 hour) recovery and recuperation from the effects of acute alcohol or drug intoxication. Sobering centers are fully staffed facilities providing oversight and ongoing monitoring throughout the sobering process.
These adverse effects are believed to be due to the neurotoxic effects of repeated withdrawal from alcohol on aberrant neuronal plasticity and cortical damage. Repeated periods of acute intoxication followed by acute detoxification has profound effects on the brain and is associated with an increased risk of seizures as well as cognitive deficits.
The CDC also says that more than 2,000 Americans die each year from acute alcohol intoxication, and that more than 38 million American adults admit to binge-drinking once a week, downing eight ...
Substance intoxication is a transient condition of altered consciousness and behavior associated with recent use of a substance. [1] It is often maladaptive and impairing , but reversible. [ 2 ] If the symptoms are severe, the term "substance intoxication delirium " may be used. [ 3 ]
Acute alcohol intoxication through excessive doses in general causes short- or long-term health effects. NMDA receptors become unresponsive, slowing areas of the brain for which they are responsible. Contributing to this effect is the activity that alcohol induces in the gamma-aminobutyric acid (GABA) system. The GABA system is known to inhibit ...
Acute intoxication, such as binge drinking and alcoholism, are known potent risk factors for suicide. [31] Binge drinking is also associated with an increased risk of unplanned and unprotected sex , unplanned pregnancies , and an increased risk of HIV infection. 10% of women and 19% of men have reported being assaulted as a result of alcohol.