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Metadoxine, also known as pyridoxine-pyrrolidone carboxylate, is a drug used to treat chronic and acute alcohol intoxication. [1] Metadoxine accelerates alcohol clearance from the blood. [2] Metadoxine is an ion pair salt of pyridoxine and pyrrolidone carboxylate (PCA). [1]
Several well-known criteria can be used to establish a probable diagnosis. For a physician in the acute-treatment setting, acute alcohol intoxication can mimic other acute neurological disorders or is frequently combined with other recreational drugs that complicate diagnosis and treatment.
A sobering center is a facility or setting providing short-term (4-12 hour) recovery and recuperation from the effects of acute alcohol or drug intoxication. Sobering centers are fully staffed facilities providing oversight and ongoing monitoring throughout the sobering process.
Substance intoxication is a transient condition of altered consciousness and behavior associated with recent use of a substance. [1] It is often maladaptive and impairing , but reversible. [ 2 ] If the symptoms are severe, the term "substance intoxication delirium " may be used. [ 3 ]
As of 2020, Alcohol-related brain damage (ARBD) is studied to affect roughly one in 200 members of the general adult population. Young adults are disproportionately represented among this ...
These adverse effects are believed to be due to the neurotoxic effects of repeated withdrawal from alcohol on aberrant neuronal plasticity and cortical damage. Repeated periods of acute intoxication followed by acute detoxification has profound effects on the brain and is associated with an increased risk of seizures as well as cognitive deficits.
Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
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related to: acute alcohol intoxication treatment guidelines ohio