Search results
Results from the WOW.Com Content Network
The reaction of an organic substrate with phosgene is called phosgenation. [9] Phosgenation of diols give carbonates (R = H, alkyl, aryl), which can be either linear or cyclic: n HO−CR 2 −X−CR 2 −OH + n COCl 2 → [−O−CR 2 −X−CR 2 −O−C(=O)−] n + 2n HCl. An example is the reaction of phosgene with bisphenol A to form ...
Phosgene (carbonyl dichloride, Cl–CO–Cl) is a very toxic gas that is the dichloride of carbonic acid (HO–CO–OH). Both chlorine atoms in phosgene can undergo reactions analogous to the preceding reactions of acyl halides. Phosgene is used a reactant in the production of polycarbonate polymers, among other industrial applications.
The main polycarbonate material is produced by the reaction of bisphenol A (BPA) and phosgene COCl 2. The overall reaction can be written as follows: The first step of the synthesis involves treatment of bisphenol A with sodium hydroxide, which deprotonates the hydroxyl groups of the bisphenol A. [6] (HOC 6 H 4) 2 CMe 2 + 2 NaOH → Na 2 (OC 6 ...
Phosgene oxime, or CX, is an organic compound with the formula Cl 2 C=N−O H. It is a potent chemical weapon, specifically a nettle agent. The compound itself is a colorless solid, but impure samples are often yellowish liquids. It has a strong, disagreeable and irritating odor. It is used as a reagent in organic chemistry. [2]
Sodium hydroxide, also known as lye and caustic soda, [1] [2] is an inorganic compound with the formula NaOH.It is a white solid ionic compound consisting of sodium cations Na + and hydroxide anions OH −.
The net reaction is as follows: 2 PhOH + COCl 2 → PhOCO 2 Ph + 2 HCl. The use of phosgene can be avoided by the oxidative carbonylation of phenol with carbon monoxide: [2] 2 PhOH + CO + [O] → PhOCO 2 Ph + H 2 O. Dimethyl carbonate can also be transesterified with phenol: CH 3 OCO 2 CH 3 + 2 PhOH → PhOCO 2 Ph + 2 MeOH
The reaction between an acid halide and a Gilman reagent is not a nucleophilic acyl substitution reaction, however, and is thought to proceed via a radical pathway. [26] The Weinreb ketone synthesis can also be used to convert acid halides to ketones. In this reaction, the acid halide is first converted to an N–methoxy–N–methylamide ...
The reaction proceeds through generation of an acylium center. The reaction is completed by deprotonation of the arenium ion by AlCl 4 −, regenerating the AlCl 3 catalyst. However, in contrast to the truly catalytic alkylation reaction, the formed ketone is a moderate Lewis base, which forms a complex with the strong Lewis acid aluminum ...