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Ciclosporin (cyclosporine, Neoral): Blood levels of ciclosporin are increased if taken with grapefruit juice, orange juice, or apple juice. [12] A plausible mechanism involves the combined inhibition of enteric CYP3A4 and MDR1, which potentially leads to serious adverse events (e.g., nephrotoxicity).
For example, Natalie’s orange juice and Simply orange juice both are made with just one ingredient (oranges) and have no added sugar—although there is sugar from the oranges. These are the ...
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. [7] Although used to treat high blood pressure, it does not seem to improve mortality in those with the condition. [8] [9] Other uses include the prevention of migraines and treatment of certain irregular heart beats.
Interactions with other foods (e.g., grapefruit juice, pomello, cranberry juice, brassica vegetables) Transporters: Substrate of efflux transporters (e.g. P-glycoprotein) Health of the gastrointestinal tract; Enzyme induction/inhibition by other drugs/foods:
Orange or grapefruit juice The citrus juices are very high in vitamin C, so they’re pretty popular, Young says. She’s partial to grapefruit juice, but cautions people to be aware of its ...
A New York man who previously bought Simply Tropical juice is suing Coca-Cola and the Simply Orange Juice Co., which is owned by Coca-Cola, alleging false and deceptive advertising when it comes ...
The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...
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