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Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, trifacial neuralgia, or suicide disease, is a long-term pain disorder that affects the trigeminal nerve, [7] [1] the nerve responsible for sensation in the face and motor functions such as biting and chewing.
The trigeminal nerve.. ATN is usually attributed to inflammation or demyelination, with increased sensitivity of the trigeminal nerve.These effects are believed to be caused by infection, demyelinating diseases, or compression of the trigeminal nerve (by an impinging vein or artery, a tumor, dental trauma, accidents, or arteriovenous malformation) and are often confused with dental problems.
Improvement can be seen in an average of 1.7 weeks for episodic cluster headache and 5 weeks for chronic cluster headache when using a dosage of ranged between 160 and 720 mg (mean 240 mg/day). [50] Preventive therapy with verapamil is believed to work because it has an effect on the circadian rhythm and on CGRPs.
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life [9], and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
Acute pain due to trigeminal neuralgia is usually successfully treated with anticonvulsants such as carbamazepine [155] or phenytoin. [156] [157] [158] Both Lhermitte's sign and painful dysesthesias usually respond to treatment with carbamazepine, clonazepam, [159] or amitriptyline.
The superior cerebellar artery is frequently the cause of trigeminal neuralgia. It compresses the trigeminal nerve (CN V), causing pain on the patient's face (the distribution of the nerve). This may be treated with vascular microsurgery to decompress the trigeminal nerve. [2] At autopsy, 50% of people without trigeminal neuralgia will also be ...
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