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In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
Cannabis is the most widely used illicit drug in the Western world. [3] In the United States, 10-20% of those who begin the use of cannabis daily will later become dependent. [4] [5] Cannabis use can lead to addiction, which is defined as "when the person cannot stop using the drug even though it interferes with many aspects of his or her life."
Marijuana causes psychological impairment; Marijuana interferes with male and female sex hormones; Marijuana use during pregnancy damages the fetus; Marijuana impairs the immune system; Marijuana is more damaging to the lungs than tobacco; Marijuana gets trapped in body fat; Marijuana-related hospital emergencies are increasing
Many health conditions can cause joint pain as a symptom. ... pad with a source of cold like an ice pack. Joint pain from a mild injury ... loss of 10 to 20 percent of baseline body weight had ...
Early findings from a large Danish study last year found that using medical marijuana for chronic pain was associated with a 64% increase in the risk of abnormal heart rhythms such as atrial ...
While cannabis may have potential for refractory cancer pain or use as an antiemetic, much of the evidence comes from outdated or small studies, or animal experiments. [ 24 ] Although there is ongoing research, claims that cannabis has been proved to cure cancer are, according to Cancer Research UK , both prevalent on the internet and "highly ...
Medical cannabis can be administered through various methods, including capsules, lozenges, tinctures, dermal patches, oral or dermal sprays, cannabis edibles, and vaporizing or smoking dried buds. Synthetic cannabinoids are available for prescription use in some countries, such as synthetic delta-9-THC and nabilone.
It can also cause depression or depressive symptoms and anxiety in some individuals. [ 25 ] [ 26 ] Long-term side effects include Cushing's syndrome , steroid dementia syndrome , [ 27 ] truncal weight gain, glaucoma and cataracts , diabetes mellitus type 2 , and depression upon dose reduction or cessation. [ 28 ]