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Signs and symptoms of ACEi and ARB use during pregnancy include kidney damage or failure, oligohydramnios, anuria, joint contractures, and hypoplasia of the skull. [58] Common, alternative agents for high blood pressure in pregnant women include anti-adrenergic and beta-blocking medications, such as methyldopa or metoprolol, respectively.
Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12] Avoid use during pregnancy as it may cause vasoconstriction of uterine arteries thus reducing fetal blood supply. [14] Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines
[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]
Use during breastfeeding appears to be safe. [4] Paromomycin is in the aminoglycoside family of medications and causes microbe death by stopping the creation of bacterial proteins. [3] Paromomycin was discovered in the 1950s from a type of streptomyces and came into medical use in 1960.
Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical nasal decongestant. [1] Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. [2]
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
Acetaminophen has long been considered safe to help reduce fever and relieve pain while pregnant. Here's what experts say about new claims.
It is unclear if use during pregnancy or breastfeeding is safe. [4] It is an antihistamine and mast cell stabilizer. [5] [2] Olopatadine was patented in 1986 and came into medical use in 1997. [6] It is available as a generic medication. [2]
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