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Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
The Schilling test was a medical investigation used for patients with vitamin B 12 (cobalamin) deficiency. [1] The purpose of the test was to determine how well a patient is able to absorb B12 from their intestinal tract. The test is now considered obsolete and is rarely performed, and is no longer available at many medical centers.
Blood tests may show low levels of vitamin B 12, elevated levels of methylmalonic acid or homocysteine, and a routine complete blood counts may shows anemia with an elevated mean cell volume. [140] The presence of antibodies to gastric parietal cells and intrinsic factor may indicate pernicious anemia .
First, have your health care provider run blood tests to see if you truly have a B12 deficiency. If you do, the only way to treat it is to consume more B12, either through food, supplements or ...
Most adults need 2.4 micrograms of vitamin B12 a day, although the numbers are slightly higher during pregnancy and breastfeeding. Causes of vitamin B12 deficiency There are a few reasons why ...
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