Search results
Results from the WOW.Com Content Network
Papillon–Lefèvre syndrome (PLS), also known as palmoplantar keratoderma with periodontitis, [1] [2] is an autosomal recessive [3] genetic disorder caused by a deficiency in cathepsin C. [ 4 ] [ 5 ]
Haim–Munk syndrome (also known as "palmoplantar keratoderma with periodontitis and arachnodactyly, acro-osteolysis and Cochin Jewish syndrome" [1]) is a skin disease caused, like Papillon–Lefèvre syndrome, by a mutation in the cathepsin C gene. [1] One of its features is thick curved finger and toenails. [2]
Orofaciodigital syndrome 1 (OFD1), also called Papillon-Léage and Psaume syndrome, [1] is an X-linked congenital disorder characterized by malformations of the face, oral cavity, and digits with polycystic kidney disease and variable involvement of the central nervous system.
The bone destruction patterns that occur as a result of periodontal disease generally take on characteristic forms. This X-ray film displays a horizontal defect . This X-ray film displays two lone-standing mandibular teeth, #21 and #22: the lower left first premolar and canine, exhibiting severe bone loss of 30-50%.
[1] [2] At least 16 systemic diseases have been linked to periodontitis. These systemic diseases are associated with periodontal disease because they generally contribute to either a decreased host resistance to infections or dysfunction in the connective tissue of the gums , increasing patient susceptibility to inflammation-induced destruction.
Here are links to possibly useful sources of information about Papillon–Lefèvre syndrome. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
For premium support please call: 800-290-4726 more ways to reach us
Genodermatosis is a hereditary skin disease with three inherited modes including single gene inheritance, multiple gene inheritance and chromosome inheritance. [1] There are many different types of genodermatosis; the prevalence of genodermatosis ranges from 1 per 6000 people to 1 per 500,000 people. [2]