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Oxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. [ 1 ] [ 2 ] It is usually white to yellowish in appearance, and may take the form of a powder, tablet or paste.
Praziquantel is well absorbed (about 80%) from the gastrointestinal tract. However, due to extensive first-pass metabolism, only a relatively small amount enters systemic circulation. Praziquantel has a serum half-life of 0.8 to 1.5 hours in adults with normal renal and liver function. Metabolites have a half-life of 4 to 5 hours.
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Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass dewormings; Drugs not members of these three main categories include: Diethylcarbamazine – effective against Wuchereria bancrofti, Brugia malayi, Brugia timori ...
This strategy is now recommended by most veterinarians and parasitologists, as it reduces the probability of resistance. For horses that are consistently deemed "low shedders," it is still recommended to deworm at least 1–2 times per year with ivermectin + praziquantel or moxidectin + praziquantel to target tapeworms, bots, and small strongyles.
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
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