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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
[7] [5] [6] Estradiol acetate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [8] [9] It is an estrogen ester and a prodrug of estradiol in the body. [9] [8] Because of this, it is considered to be a natural and bioidentical form of estrogen. [9] [10]
High-dose estrogen therapy has been used successfully in the treatment of sexual deviance such as paraphilias in men. [ 45 ] [ 46 ] However, it has been found to produce many side effects (e.g., gynecomastia , feminization , cardiovascular disease , blood clots ), and so is no longer recommended for such purposes. [ 45 ]
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men.
[62] [63] [64] Conversely, research on combined estrogen and progestogen therapy for depressive symptoms in menopausal women is scarce and inconclusive. [ 62 ] [ 63 ] Some researchers contend that progestogens have an adverse influence on mood and reduce the benefits of estrogens on mood, [ 65 ] [ 66 ] [ 2 ] whereas other researchers maintain ...
One study’s findings suggest that cruciferous vegetables such as broccoli, cauliflower, and kale may help lower blood pressure in adults with mild hypertension, pointing to another potential ...
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
Estrogen also plays very important role in animal metabolism balance. These unexpected diseases hindered estrogen to get involved in neurodegenerative disease therapy. So, when applying estrogen-like drugs to relieve neurodegenerative diseases, the concentration should be restrictly controlled to avoid these side effects. [citation needed]
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