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The disease was first described as a distinctive disease by Emil Kraepelin after suppressing some of the clinical (delusions and hallucinations) and pathological features (arteriosclerotic changes) contained in the original report of Auguste D. [248] He included Alzheimer's disease, also named presenile dementia by Kraepelin, as a subtype of ...
Here are 10 early signs and symptoms of Alzheimer's, according to the Alzheimer's Association. If you notice any of these signs in a loved one, schedule an appointment with their doctor.
While research is still being done to understand exactly how to treat Alzheimer's, the first step is understanding what is happening in the brain that causes it in the first place.
The symptoms of Alzheimer's disease as a distinct nosologic entity were first identified by Emil Kraepelin, who worked in Alzheimer's laboratory, and the characteristic neuropathology was first observed by Alois Alzheimer in 1906. Because of the overwhelming importance Kraepelin attached to finding the neuropathological basis of psychiatric ...
Alzheimer's disease is a progressive disease that triggers brain cell deterioration. Over time, this makes things like remembering, learning, controlling emotions, and even basic tasks difficult ...
In 2009 this drug was in phase III clinical trials for use in Alzheimer's disease, and also phase II clinical trials for use in Huntington's disease. [61] In March 2010, the results of a clinical trial phase III were released; the investigational Alzheimer's disease drug Dimebon failed in the pivotal CONNECTION trial of patients with mild-to ...
“A study from 2019 reported that a woman carrying the presenilin 1 (PSEN1) mutation, a genetic cause of early-onset Alzheimer’s disease, did not develop dementia in her 40s as others with the ...
Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease. ARIA is associated with anti-amyloid drugs, particularly human monoclonal antibodies such as aducanumab. [1] There are two types of ARIA: ARIA-E and ARIA-H.
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