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A genetically modified virus is a virus that has been altered or generated using biotechnology methods, and remains capable of infection.Genetic modification involves the directed insertion, deletion, artificial synthesis or change of nucleotide bases in viral genomes.
Synthetic virology is a branch of virology engaged in the study and engineering of synthetic man-made viruses.It is a multidisciplinary research field at the intersection of virology, synthetic biology, computational biology, and DNA nanotechnology, from which it borrows and integrates its concepts and methodologies.
Recombinant adeno-associated virus (rAAV) based genome engineering is a genome editing platform centered on the use of recombinant AAV vectors that enables insertion, deletion or substitution of DNA sequences into the genomes of live mammalian cells.
Virus nanotechnology is the use of viruses as a source of nanoparticles for biomedical purposes. Viruses are made up of a genome and a capsid; and some viruses are enveloped. Most virus capsids measure between 20-500 nm in diameter. Because of their nanometer size dimensions, viruses have been considered as naturally occurring nanoparticles.
The use of engineered plant viruses has been proposed to enhance crop performance and promote sustainable production. [12] Replicating virus-based vectors are typically used. [63] RNA viruses used for monocots include wheat streak mosaic virus and barley stripe mosaic virus and, for dicots, tobacco rattle virus.
Virus crystallisation is the re-arrangement of viral components into solid crystal particles. [1] The crystals are composed of thousands of inactive forms of a particular virus arranged in the shape of a prism. [2] The inactive nature of virus crystals provide advantages for immunologists to effectively analyze the structure and function behind ...
A virus with this "viral envelope" uses it—along with specific receptors—to enter a new host cell. Viruses vary in shape from the simple helical and icosahedral to more complex structures. Viruses range in size from 20 to 300 nanometres; it would take 33,000 to 500,000 of them, side by side, to stretch to 1 centimetre (0.4 in).
Scientists often look to the genomes of Metavirus to compare nucleic acid sequences to the sequences of other viruses, constructing lineages and proposing common ancestors. [ citation needed ] Multiple taxa of Metavirus have genomic sequence that are homologous to other genera of Metaviridae and a suggest common ancestor and/or coevolution. [ 10 ]