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However, the neurotoxic side effects occurring at the required dosages have prevented the widespread use of metronidazole as an adjuvant agent in radiation therapy. [32] However, other nitroimidazoles derived from metronidazole such as nimorazole with reduced electron affinity showed less serious neuronal side effects and have found their way ...
Side effects [ edit ] Though an effective antibiotic when all others fail, against extremely drug resistant infections, it has many side effects. including inhibition of monoamine oxidase , [ 1 ] and as with other nitrofurans generally, minimum inhibitory concentrations also produce systemic toxicity, resulting in tremors, convulsions ...
Common side effect is darkening of the tongue and teeth. [58] It also causes darkening of faeces which may confuse with the signs of gastrointestinal bleeding. [ 59 ] In renal failure patients, long-term use of bismuth may cause toxicity, resulting in encephalopathy ( ataxia , headache, confusion , seizures).
Side effects of alcohols applied to the skin include skin irritation. [2] Care should be taken with electrocautery, as ethanol is flammable. [1] Types of alcohol used include ethanol, denatured ethanol, 1-propanol, and isopropyl alcohol. [6] [7] Alcohols are effective against a range of microorganisms, though they do not inactivate spores. [7]
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
These effects are known from the drug's components as well as from other antibiotics. A very rare but dangerous reaction is Stevens–Johnson syndrome, a life-threatening condition affecting the skin, which has also been described under metronidazole and tetracycline as separate drugs. [3]
For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild side effects. [3] Side effects may include flatulence, vomiting, and itchiness. [1] During pregnancy it is recommended that it be taken after the first trimester. [1]
The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...
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