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Estrone sulfate, also known as E1S, E1SO4 and estrone 3-sulfate, is a natural, endogenous steroid and an estrogen ester and conjugate. [1] [2] [3]In addition to its role as a natural hormone, estrone sulfate is used as a medication, for instance in menopausal hormone therapy; for information on estrone sulfate as a medication, see the estrone sulfate (medication) article.
Equine estrogens, or horse estrogens, are estrogens found in horses. [1] [2] [3] They include the following: ... Estrone sulfate: E1S; Estrone 3-sulfate <1 <1 >10 >10 ...
[6] [4] [1] [7] It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and equilin sulfate. [ 1 ] [ 7 ] [ 6 ] CEEs are available in the form of both natural preparations manufactured from the urine of pregnant mares and fully synthetic replications of the natural preparations.
Equilin, also known as δ 7-estrone or as 7-dehydroestrone, as well as estra-1,3,5(10),7-tetraen-3-ol-17-one, is a naturally occurring estrane steroid and an analogue of estrone. [ 2 ] [ 3 ] In terms of chemical structure and pharmacology , equilin is to 17β-dihydroequilin (δ 7 -17β-estradiol) as estrone is to estradiol .
8,9-Dehydroestrone, or Δ 8-estrone, also known as estra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses which is closely related to equilin, equilenin, and estrone, and, as the 3-sulfate ester sodium salt, is a minor constituent (3.5%) of conjugated estrogens (Premarin).
Estrone, also known as estra-1,3,5(10)-trien-3-ol-17-one, is a naturally occurring estrane steroid with double bonds at the C1, C3, and C5 positions, a hydroxyl group at the C3 position, and a ketone group at the C17 position. The name estrone was derived from the chemical terms estrin (estra-1,3,5(10)-triene) and ketone.
8,9-Dehydroestradiol, or Δ 8-17β-estradiol, also known as estra-1,3,5(10),8-tetraen-17β-ol-3-one, is a naturally occurring steroidal estrogen found in horses which is closely related to equilin, equilenin, and estradiol, and, as the 3-sulfate ester sodium salt, is a minor constituent of conjugated estrogens (Premarin). [1]
Estrone sulfate (E1S) is an estrogen medication and naturally occurring steroid hormone. [1] It is used in menopausal hormone therapy among other indications. [ 1 ] [ 2 ] As the sodium salt (sodium estrone sulfate), it is the major estrogen component of conjugated estrogens (Premarin) and esterified estrogens (Estratab, Menest).