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Some studies showed a low vaccination rate against some Vaccine-preventable disease among patients taking immunosuppressive drugs, despite a generally positive attitude towards vaccinations. [13] There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver injury and kidney ...
Azathioprine, sold under the brand name Imuran, among others, is an immunosuppressive medication. [5] It is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus, and in kidney transplants to prevent rejection.
Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. [1] [2] In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant. [3]
Leflunomide, sold under the brand name Arava among others, is an immunosuppressive disease-modifying antirheumatic drug , [8] used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. [9] Bottle of Leflunomide (Arava) and tablet
Generally, drugs outlined within the ATC code L04 should be included in this category. Please see WP:PHARM:CAT for more information. Wikimedia Commons has media related to Immunosuppressants .
It was approved for medical use in the United States in 1995 following the discovery of its immunosuppressive properties in the 1990s. [13] [14] It is available as a generic medication. [16] In 2022, it was the 227th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [17] [18]
No systematic studies of adverse effects under diroximel fumarate are available. The most common side effects in studies with dimethyl fumarate were flushing (in 34% of patients treated with the drug, versus 5% in the placebo group) and gastrointestinal effects such as diarrhoea (14% versus 10%), nausea (12% versus 9%), abdominal pain (9% versus 4%), vomiting (8% versus 5%), and indigestion (5 ...
The most common side effects are upper respiratory tract infection (nose and throat infection), nasopharyngitis (inflammation of the nose and throat) and headache. [ 8 ] [ 7 ] The most serious side effect is meningococcal infection , a bacterial infection caused by Neisseria meningitidis that can cause meningitis and sepsis .
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