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Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
Long COVID is a patient-created term coined early in the pandemic by those suffering from long-term symptoms. [12] [13] While long COVID is the most prevalent name, the terms long-haul COVID, post-COVID-19 syndrome, post-COVID-19 condition, [1] [14] post-acute sequelae of COVID-19 (PASC), and chronic COVID syndrome are also in use. [5]
What you need to know about the signs and symptoms, causes, and treatment options for the rare neurological disease.
While it is commonly assumed that people either recover or die from infections, long-term symptoms—or sequelae—are a possible outcome as well. [1] Examples include long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC), Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and post-Ebola virus syndrome. [1]
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
The Canadian Consensus Criteria require "post exertional malaise and/or [post exertional] fatigue" instead. [21] [22] [23] [19] [24] On the other hand, the older Oxford Criteria lack any mention of PEM, [25] and the Fukuda Criteria consider it optional. Depending on the definition of ME/CFS used, PEM is present in 60 to 100% of ME/CFS patients. [6]
The estimates depend on the definition of long COVID, the population studied, [17] as well as a number of other methodological differences, such as whether a comparable cohort of individuals without COVID-19 were included, [18] what kinds of symptoms are considered representative of long COVID, [18] and whether long COVID is assessed through a ...