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The following are settlements reached with US authorities against pharmaceutical companies to resolve allegations of "off-label" promotion of drugs. Under the Federal Food, Drug, and Cosmetic Act, it is illegal for pharmaceutical companies to promote their products for uses not approved by the Food and Drug Administration (FDA), and corporations that market drugs for off-label indications may ...
Chemical structure of modafinil. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives. These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
In a 2006 study, a single dose of modafinil 200 mg caused a decrease in blood prolactin levels, although it did not affect human growth hormone or thyroid-stimulating hormone. [87] [143] Since modafinil induces the activity of the CYP3A4 enzyme involved in cortisol clearance, [144] modafinil may reduce the bioavailability of hydrocortisone ...
The clinic also spent nearly $100,000 during that period on Provigil, a stimulant that is “55 times more expensive than the generic equivalent,” the report said.
A Cephalon-founded study in which patients were administered modafinil, methylphenidate, and a placebo found that modafinil produces "psychoactive and euphoric effects and feelings consistent with [methylphenidate]." [12] Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes.
Complaints lodged with the BBB fell about 7%, to 927,000. In practical terms, those numbers suggest that more Americans are being smart about their shopping, looking into businesses' reputations ...
8 warning signs of a debt collector scam Receiving a call, email or letter from a company purporting to be a debt collector can spark alarm. Before disclosing any information, look for these eight ...
In the United States military, modafinil has been approved for use on certain Air Force missions, and it is being investigated for other uses. [19] As of November 2012, modafinil is the only drug approved by the Air Force as a "go pill" for fatigue management. [20] The use of dextroamphetamine (a.k.a., Dexedrine) is no longer approved. [20] Yes ...
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