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Sodium lauryl sulfoacetate (SLSA) or lathanol is an organic compound used in many cleaning and hygiene products as an anionic surfactant. [1] Also it is used as in sodium citrate/sodium lauryl sulfoacetate/glycerol laxative products.
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula CH 3 (CH 2) 11 OSO 3 Na and structure H 3 C−(CH 2) 11 −O−S(=O) 2 −O − Na +. It is an anionic surfactant used in many cleaning and hygiene products. This compound is the sodium salt of the 12 ...
Sodium citrate/sodium lauryl sulfoacetate/glycerol sold under the brandname Microlax and Micolette Micro enema, among others, is a small tube of liquid gel that is used to treat constipation. [ 1 ] The main active ingredients are sodium lauryl sulfoacetate (0.90% w/v ), sodium citrate (9.0% w/v ) and glycerol .
A common example is sodium lauryl sulfate, with the formula CH 3 (CH 2) 11 OSO 3 Na. Also common in consumer products are the sulfate esters of ethoxylated fatty alcohols such as those derived from lauryl alcohol. An example is sodium laureth sulfate, an ingredient in some cosmetics. [2]
Sulfation is widely used in the production of consumer products such as detergents, shampoos, and cosmetics. Since the sulfate group is highly polar, its conjugation to a lipophilic "tail" gives surfacant-like properties. Well known sulfates are sodium lauryl sulfate and sodium laureth sulfate. [2]
As to whether these alternatives are "milder" or otherwise preferrable for each specific application, I don't think solid research is available. But since some consumers prefer "SLS-free" products, the market delivers. "Sodium lauryl sulfoacetate" is chemically different from Sodium lauryl sulfate though, no doubt about that.
Micolette Micro-enema® contains 45 mg sodium lauryl sulphoacetate, 450 mg per 5 ml sodium citrate BP, and 625 mg glycerol BP [48] and is a small volume stimulant enema suitable where large-volume enemas are contra-indicated.