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2. Huntington's disease - Wikipedia

   en.wikipedia.org/wiki/Huntington's_disease

   The differing functions of these proteins are the cause of pathological changes, which in turn cause the disease symptoms. The Huntington's disease mutation is genetically dominant and almost fully penetrant; mutation of either of a person's HTT alleles causes the disease. It is not inherited according to sex, but by the length of the repeated ...

3. Medical mystery solved: Why do some people develop Huntington ...

   www.aol.com/news/medical-mystery-solved-why...

   Huntington's disease, which affects about 30,000 Americans, is a fatal, inherited disorder that causes progressive movement, psychological and cognitive problems. If a parent has it, their ...

4. Dementia - Wikipedia

   en.wikipedia.org/wiki/Dementia

   Huntington's disease is a neurodegenerative disease caused by mutations in a single gene HTT, that encodes for huntingtin protein. Symptoms include cognitive impairment and this usually declines further into dementia. [86] The first main symptoms of Huntington's disease often include: difficulty concentrating; memory lapses

5. Neurodegenerative disease - Wikipedia

   en.wikipedia.org/wiki/Neurodegenerative_disease

   Parkinson's disease and Huntington's disease are both late-onset and associated with the accumulation of intracellular toxic proteins. Diseases caused by the aggregation of proteins are known as proteopathies, and they are primarily caused by aggregates in the following structures: [9] cytosol, e.g. Parkinson's and Huntington's

6. Cognitive disorder - Wikipedia

   en.wikipedia.org/wiki/Cognitive_disorder

   The main causes are neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease because they affect or deteriorate brain functions. [7] Other diseases and conditions that cause NCDs include vascular dementia , frontotemporal degeneration , Lewy body disease , prion disease , normal pressure ...

7. Subcortical dementia - Wikipedia

   en.wikipedia.org/wiki/Subcortical_dementia

   The dementia [2] is more severe in patients with early onset of Huntington's disease. Parkinson's disease is characterised by features of dementia in older age. [ 3 ] [ 4 ] The adult type " leukodystrophy " also causes subcortical dementia with prominent frontal lobe features.