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Watson and Crick used many aluminium templates like this one, which is the single base Adenine (A), to build a physical model of DNA in 1953. When Watson and Crick produced their double helix model of DNA, it was known that most of the specialized features of the many different life forms on Earth are made possible by proteins.
Francis Harry Compton Crick OM FRS [3] [4] (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist.He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule.
Based on the Watson-Crick model, he envisaged that the DNA itself is a direct template for protein synthesis. [18] Assuming that the four bases of DNA could produce 20 different combinations as triplets, he suggested that the different amino acids must correspond to a twenty-letter alphabet of the nucleotide sequence. [19]
James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist.In 1953, he co-authored with Francis Crick the academic paper in Nature proposing the double helix structure of the DNA molecule. [10]
Watson and Crick used characteristics and features of Photo 51, together with evidence from multiple other sources, to develop the chemical model of the DNA molecule. Their model, along with papers by Wilkins and colleagues, and by Gosling and Franklin, were first published, together, in 1953, in the same issue of Nature. In 1962, the Nobel ...
On April 25, 1953 James D. Watson and Francis Crick published "a radically different structure" for DNA, [3] thereby founding the field of molecular genetics. Their structural model featured two strands of complementary base-paired DNA, running in opposite directions as a double helix. They concluded their report saying that "It has not escaped ...
Wilkins continued to test, verify, and make significant corrections to the Watson–Crick DNA model and to study the structure of RNA. [10] Wilkins, Crick, and Watson were awarded the 1962 Nobel Prize for Physiology or Medicine, "for their discoveries concerning the molecular structure of nucleic acids and its significance for information ...
James Michael Creeth (3 October 1924 – 15 January 2010) was an English biochemist whose experiments on DNA viscosity confirming the existence of hydrogen bonds between the purine and pyrimidine bases of DNA were crucial to Watson and Crick's discovery of the double helix structure of DNA.
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