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A study published in November 2024 in Nature found that adipose (fat) tissue cells retain a memory of obesity even after weight loss, which could contribute to the yo-yo weight loss effect ...
Obesity can increase the risk for a host of health issues including heart disease, sleep apnea, and type 2 diabetes. Obesity also causes chronic low-grade inflammation. This type of inflammation ...
Being overweight in midlife has been linked to greater risk of developing Alzheimer’s disease or dementia, and a new study shows that brain changes in obese people mirror some of those with ...
Pathophysiology of obesity is the study of disordered physiological processes that cause, result from, or are otherwise associated with obesity. A number of possible pathophysiological mechanisms have been identified which may contribute in the development and maintenance of obesity.
Stimulation of the melanocortin-4 receptor causes a decrease in appetite and an increase in metabolism of fat and lean body mass, even in a relatively starved state. [21] Conversely, damage to this receptor has been shown to result in morbid obesity, and is the most commonly known cause of monogenic morbid obesity. [22]
Obesity is a medical condition, sometimes considered a disease, [8] [9] [10] in which excess body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over 30 kg / m 2 ...
Obesity is associated with many adverse effects physically and mentally. These include memory deficits. Obesity causes an increase in inflammation throughout the body. [81] Cytokines, the chemicals that regulate this, can cross the blood-brain barrier in certain cases and affect the brain, including memory related areas. [82]
The physicians tied a specific type of body fat, known as visceral fat, to higher levels of abnormal proteins in the brain that are indicators of Alzheimer’s. Visceral fat builds up around and ...