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Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life—effects sufficiently ...
Phineas Gage Skull of Phineas Gage. The Warren Anatomical Museum, housed within Harvard Medical School's Countway Library of Medicine, was founded in 1847 by Harvard professor John Collins Warren, [1] whose personal collection of 160 [2] unusual and instructive anatomical and pathological specimens now forms the nucleus of the museum's 15,000-item collection. [3]
Phineas Gage, who sustained a severe frontal lobe injury in 1848, has been called a case of dysexecutive syndrome. Gage's psychological changes are almost always exaggerated – of the symptoms listed, the only ones Gage can be said to have exhibited are "anger and frustration", slight memory impairment, and "difficulty in planning". [21]
John Martyn Harlow (1819–1907) was an American physician primarily remembered for his attendance on brain-injury survivor Phineas Gage, and for his published reports on Gage's accident and subsequent history. Boston Herald, May 20, 1907. Harlow was born in Whitehall, New York on November 25, 1819 to Ransom and Annis Martyn Harlow. [1]
A widely reported case of frontal lobe injury was that of Phineas Gage, a railroad worker whose left frontal lobe was damaged by a large iron rod in 1848 (though Gage's subsequent personality changes are almost always grossly exaggerated).
The first case study on Phineas Gage's head injury is one of the most astonishing brain injuries in history. In 1848, Phineas Gage was paving way for a new railroad line when he encountered an accidental explosion of a tamping iron straight through his frontal lobe.
While working on the Rutland & Burlington railroad in Cavendish, Vermont, with his former physics teacher Hosea Doton, [3] he was the first physician to treat railroad contractor Phineas Gage after Gage survived accidentally blasting a tamping iron through his jaw and skull while setting an explosive charge. [4]
A famous example is Phineas Gage, whose personality appears to have changed (though not as dramatically as usually described) after a perforating injury to his frontal lobe(s). People with subarachnoid hemorrhage, a blown pupil, respiratory distress, hypotension, or cerebral vasospasm are more likely to have worse outcomes. [5]