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  2. Anti-dsDNA antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-dsDNA_antibodies

    Anti-double stranded DNA (Anti-dsDNA) antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories.

  3. Antinuclear antibody - Wikipedia

    en.wikipedia.org/wiki/Antinuclear_antibody

    Anti-double stranded DNA (anti-dsDNA) antibodies are highly associated with SLE. They are a very specific marker for the disease, with some studies quoting nearly 100%. [8] Data on sensitivity ranges from 25 to 85%. Anti-dsDNA antibody levels, known as titres, correlate with disease activity in SLE; high levels indicate more active lupus.

  4. Anti-histone antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-histone_antibodies

    Anti-histone antibodies can be clinically detected using an ELISA assay. A blood sample is required for the test. [9] [5] Indirect immunofluorescence can also be used to detect anti-histone antibodies. Homogeneous, diffuse staining indicates the presence of anti-histone antibodies, chromatin, and some double-stranded DNA. [4]

  5. Extractable nuclear antigen - Wikipedia

    en.wikipedia.org/wiki/Extractable_nuclear_antigen

    An extractable nuclear antigen panel, or an ENA panel, tests for presence of autoantibodies in the blood that react with proteins in the cell nucleus.It is usually done as a follow-up to a positive antinuclear antibody test and when one is showing symptoms of an autoimmune disorder.

  6. Undifferentiated connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Undifferentiated...

    Patients with UCTD usually have positive ANA (antinuclear antibody), and raised ESR (erythrocyte sedimentation rate) values, without typical autoantibody specificities. [14] Some 20% of the general population, [ 15 ] and up to 15% of completely healthy people, [ 16 ] test positive for ANA, but nonetheless this is regarded by some as almost ...

  7. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    Each will be present in a certain percentage of people who have a particular autoimmune disorder. For instance, up to 80% of those with SLE will have a positive double strand anti-double stranded DNA (anti-dsDNA) autoantibody test, but only about 25–30% will have a positive RNP. Some individuals who do have an autoimmune disorder will have ...

  8. Medical devices could become safer with this new breakthrough ...

    www.aol.com/medical-devices-could-become-safer...

    Hiv-positive Transplants Now Permitted For Livers And Kidneys This allows for the safer use of blood-contacting devices , such as catheters, stents, blood-oxygenation machines and dialysis ...

  9. Anti-topoisomerase antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-topoisomerase_antibodies

    Anti-topoisomerase antibodies (ATA) are autoantibodies directed against topoisomerase and found in several diseases, most importantly scleroderma. Diseases with ATA are autoimmune disease because they react with self-proteins. They are also referred to as anti-DNA topoisomerase I antibody (anti-topo I).

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