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Phenytoin may accumulate in the cerebral cortex over long periods of time which can cause atrophy of the cerebellum. The degree of atrophy is related to the duration of phenytoin treatment and is not related to dosage of the medication. [23] Phenytoin is known to be a causal factor in the development of peripheral neuropathy. [24]
Common adverse effects (1–10%), include producing too much saliva or having dry mouth, runny nose, respiratory disorders or coughing, nausea and vomiting, stomach aches, constipation or diarrhea, loss of appetite, weight gain (but the smallest risk for weight gain compared to other antipsychotics [8]), rashes, fast heart beats, blood pressure ...
“There are many medications that may cause weight gain,” says W. Scott Butsch, M.D., director of obesity medicine in the Bariatric and Metabolic Institute at the Cleveland Clinic.
Certain medications may cause weight gain or changes in body composition; these include insulin, sulfonylureas, thiazolidinediones, atypical antipsychotics, antidepressants, steroids, certain anticonvulsants (phenytoin and valproate), pizotifen, and some forms of hormonal contraception. [2]
In addition, the study was observational, meaning that it cannot prove cause, like that certain antidepressants cause weight gain or loss. Again, while researchers sought to focus on first-time ...
But serotonin is also involved in your appetite and weight control—and that may cause some people to gain weight when they take an SSRI. “There are a lot of serotonin receptors in the gut ...
As this syndrome can present secondary to multiple anticonvulsants, the general term "anticonvulsant hypersensitivity syndrome" (AHS) is favored over the original descriptive term "dilantin hypersensitivity syndrome."
Prozac was not associated with a six-month weight change, while Wellbutrin users were 15% less likely to experience a 5% weight gain. Wellbutrin continued to be associated with the least weight ...