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Trichophyton rubrum is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, [ 2 ] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot , fungal infection of nail, jock itch , and ringworm worldwide. [ 3 ]
Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia .
Athlete's foot is most commonly caused by the molds known as Trichophyton rubrum and T. mentagrophytes, [22] but may also be caused by Epidermophyton floccosum. [23] [24] Most cases of athlete's foot in the general population are caused by T. rubrum; however, the majority of athlete's foot cases in athletes are caused by T. mentagrophytes. [13]
Trichophyton mentagrophytes is a species in the fungal genus Trichophyton. [1] It is one of three common fungi which cause ringworm in companion animals.It is also the second-most commonly isolated fungus causing tinea infections in humans, and the most common or one of the most common fungi that cause zoonotic skin disease.
The most common causative organism is Trichophyton rubrum. [3] The condition is more likely to occur in people who sweat more. [4] Diagnosis is by visualization, microscopy and culture. [4] It may appear similar to dermatitis, psoriasis, keratoderma, hyperkeratosis and allergic contact dermatitis. [5]
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The disease is primarily caused by dermatophytes of the genera Trichophyton and Microsporum that invade the hair shaft. The clinical presentation is typically single or multiple patches of hair loss, sometimes with a 'black dot' pattern (often with broken-off hairs), that may be accompanied by inflammation, scaling, pustules, and itching.
Butenafine is indicated for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur, as well as athlete's foot (Tinea pedis), ringworm (Tinea corporis) and jock itch (Tinea cruris) due to Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum, and Trichophyton tonsurans.