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2. Ampicillin/sulbactam - Wikipedia

   en.wikipedia.org/wiki/Ampicillin/sulbactam

   Ampicillin/sulbactam is a combination of a β-lactam antibiotic and a β-lactamase inhibitor. Ampicillin works by binding to penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis. [13] [14] This causes disruption of the bacterial cell wall and leads to bacterial cell death.

3. List of antibiotics - Wikipedia

   en.wikipedia.org/wiki/List_of_antibiotics

   Antibiotics that cover Pseudomonas aeruginosa: Certain cephalosporins, cephalosporin-beta-lactamase-inhibitor combinations, and new siderophore cephalosporins ...

4. Ampicillin - Wikipedia

   en.wikipedia.org/wiki/Ampicillin

   Ampicillin is an antibiotic belonging to the aminopenicillin class of the penicillin family. The drug is used to prevent and treat several bacterial infections , such as respiratory tract infections , urinary tract infections , meningitis , salmonellosis , and endocarditis . [ 7 ]

5. List of β-lactam antibiotics - Wikipedia

   en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

   The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.

6. Extended-spectrum penicillin - Wikipedia

   en.wikipedia.org/wiki/Extended-spectrum_penicillin

   Aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively charged amino group does not hinder degradation by bacterially produced beta-lactamases. [ 4 ] Products

7. Gram-negative bacteria - Wikipedia

   en.wikipedia.org/wiki/Gram-negative_bacteria

   Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. [1] Their defining characteristic is their cell envelope , which consists of a thin peptidoglycan cell wall sandwiched between an inner ( cytoplasmic ) membrane and an ...

8. Pseudomonas aeruginosa - Wikipedia

   en.wikipedia.org/wiki/Pseudomonas_aeruginosa

   Pseudomonas is also a common cause of postoperative infection in radial keratotomy surgery patients. The organism is also associated with the skin lesion ecthyma gangrenosum . P. aeruginosa is frequently associated with osteomyelitis involving puncture wounds of the foot, believed to result from direct inoculation with P. aeruginosa via the ...

9. Antimicrobial spectrum - Wikipedia

   en.wikipedia.org/wiki/Antimicrobial_spectrum

   Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.