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Like Lewy bodies, Lewy neurites are a feature of α-synucleinopathies such as dementia with Lewy bodies, Parkinson's disease, and multiple system atrophy. [21] They are also found in the CA2-3 region of the hippocampus in Alzheimer's disease .
Dementia with Lewy bodies and Parkinson's disease dementia are similar in many ways, suggesting there may be a common pathophysiological mechanism, with PDD and DLB at opposite ends of a Lewy body disease spectrum, [2] and a shared component of protein deposits in Lewy bodies and Lewy neurites. [17]
Parkinson's disease dementia (PDD) is dementia that is associated with Parkinson's disease (PD). [1] Together with dementia with Lewy bodies (DLB), it is one of the Lewy body dementias characterized by abnormal deposits of Lewy bodies in the brain. [2] [3] [4] [5]
Lewy Body Dementia is a complex, challenging brain disorder that affects many parts of the brain in ways scientists are trying to better understand. One Senior Place: Lewy Body Dementia is often ...
Also known as Lewy body dementia, it is caused by clumps of protein in the brain called Lewy bodies. People with dementia with Lewy bodies share many of the same symptoms of Alzheimer’s disease ...
Dementia with Lewy bodies (DLB) is a type of dementia, a group of diseases involving progressive neurodegeneration of the central nervous system. [11] It is one of the two Lewy body dementias, along with Parkinson's disease dementia.
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